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KMID : 0032220140260030385
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Annals of Dermatology
2014 Volume.26 No. 3 p.385 ~ p.391
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Two Clinically Unusual Cases of Folliculotropic Mycosis Fungoides: One with and the Other without Syringotropism
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Bakar Ozgur
Seckin Dilek
Demirkesen Cuyan
Baykal Can
Buyukbabani Nesimi
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Abstract
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Mycosis fungoides is the most common form of cutaneous T-cell lymphoma, and it rarely exhibits predilection for hair follicle and eccrine gland infiltration. Here, we present 2 similar cases that display folliculotropism with varying amounts of follicular mucinosis, with and without syringo-tropism. The features observed in both cases were cystic, comedo-like, acneiform lesions; generalized involvement with loss of body hair; pruritus; and hidradenitis suppu-rativa-like lesions. Hypohidrosis as well as nail and palmo-plantar involvement with lichen planopilaris-like clinical features were unique characteristics of the first case. Despite the well-known aggressive behavior of follicular mycosis fungoides, the presented cases had a subtle, slowly pro-gressive, but persistent, clinical course. Folliculotropic and syringotropic mycosis fungoides are variants of cutaneous T-cell lymphoma. Clinical presentations might be chall-enging, and multiple, deep biopsy specimens containing adnexal structures are required for this critical diagnosis. Aggressive treatment may not be necessary in cases having an indolent course, especially in those with syringotropism. (Ann Dermatol 26(3) 385∼391, 2014)
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KEYWORD
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Adnexal, Eccrine gland, Follicle, Lymphoma, Mycosis fun-goides, Neoplasm
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